ABSTRACT
Background: Eclampsia is one of the most common causes of maternal and perinatal mortality and morbidity in India. Amongst the principles of management of eclampsia, the first is the control of convulsions. Magnesium sulphate is the main stay of treatment in eclampsia and imminent eclampsia. Average weight of Indian women is less than the western women due to which lower dose of magnesium sulphate can be used. The aim of the study was to compare the efficacy of low dose magnesium sulphate regimen with standard Pritchard regimen in control of eclampsia.Methods: The study was carried out at emergency labour room, GMERS Sola Civil Hospital Ahmedabad. 120 patients of eclampsia were divided randomly into study group (n=60) receiving low dose MgSO4 and control group (n=60) receiving Pritchard regimen. The recurrence of convulsion, toxicity of MgSO4 and maternal and fetal outcome was studied.Results: It was observed that with low dose MgSO4 regime, convulsions were controlled in 91.7% of the cases. With standard Pritchard’s regime convulsions were controlled in 95% of patients. The maternal and perinatal mortality and morbidity were comparable in both groups.Conclusions: Low dose magnesium sulphate therapy is as effective as Pritchard’s regime for controlling convulsions in eclampsia and can be safely given in Indian women.
ABSTRACT
Abstracts: Background: To compare the microhardness and solubility of temporary restorative materials after thermocycling. Objective is to evaluate and compare the solubility of temporary restorative materials after storage in water and to evaluate and compare micro hardness of temporary restorative materials after thermocycling. Methodology: Forty specimens will be prepared for the study. Specimens are prepared according to following four groups.(n=10). Group I – Cavit, Group II - MD Temp, Group III-Coltosol, Group IV – TMP- RS. All the temporary restorative material are manipulated according to manufacturer’s instructions in the stainless steel moulds. All the samples are measured by weight. They are stored in distilled water for 7 days and again they are measured by weight after 7 days. The change in weight is evaluated. All the samples are thermocycled at 4 & 56 degree celsius with a dwell time of 60 seconds for 100 times. After thermocycling micro hardness is calculated by Vickers hardness test of all samples. Results: The study gives highly significant result with p value less than 0.001 of both solubility and micro hardness difference as detailed below. The least solubility is with Cavit G with value 0.011 followed by Coltosol F (0.039), TMP-RS(0.054) and MD Temp(0.122). The least change in micro hardness is with Cavit-G(13.48) followed by Coltosol F(15.54), MD Temp(18.07) and TMP-RS(20.41). All values are compared using one way ANOVA (p<0.001 highly significant). Conclusion: Within the limitations of study, Cavit-G has least solubility after storage in water and highest microhardness after thermocycling among four different temporary restorative materials.